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CD3 epsilon polyclonal antibody

Product Specifications

Background

The CD3 complex mediates signal transduction. When T cells encounter antigens via the T cell receptor (TCR), information about the quantity and quality of antigens is relayed to the intracellular signal transduction machinery . This activation process depends mainly on CD3 (Cluster of Differentiation 3), a multiunit protein complex that directly associates with the TCR. CD3 is composed of four polypeptides: ζ, γ, ε and δ.

CAS Number

9007-83-4

Structure Composition

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Product Name Alternative

CD3E; T3E; T-cell surface glycoprotein CD3 epsilon chain; T-cell surface antigen T3/Leu-4 epsilon chain; CD3e

Swiss Prot

P07766

Reactivity

Human

Immunogen

A synthesized peptide derived from human CD3 epsilon

Conjugation

Unconjugated

Applications

WB, IHC-P, IP, FC

Dilution

WB: 1/500-1/1000 IHC: 1/50-1/100 IP: 1/20 FC: 1/50-1/100

Purity

Affinity Purified

Modification

Unmodified

Molecular Weight

Calculated MW: 23 kDa; Observed MW: 23 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

IgG

Applications Notes

Western blot analysis of CD3 epsilon in Jurkat lysates using CD3 epsilon antibody.

Host or Source

Rabbit

Available Sizes

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