Lamin B Receptor polyclonal antibody
Product Specifications
Background
The protein encoded by this gene belongs to the ERG4/ERG24 family. It localized in the nuclear envelope inner membrane and anchors the lamina and the heterochromatin to the membrane. It may mediate interaction between chromatin and lamin B. Mutations of this gene has been associated with autosomal recessive HEM/Greenberg skeletal dysplasia. Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been identified.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Product Name Alternative
PHA; LMN2R; TDRD18; DHCR14B; LBR
Swiss Prot
Q14739
Reactivity
Human, Rat
Immunogen
A synthesized peptide derived from human Lamin B Receptor
Conjugation
Unconjugated
Applications
WB, IHC-P, ICC/IF, IP
Dilution
WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20
Purity
Affinity Purified
Modification
Unmodified
Molecular Weight
Calculated MW: 71 kDa; Observed MW: 71 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IgG
Applications Notes
Western blot analysis of Lamin B Receptor in Jurkat lysates using Lamin B Receptor antibody.
Host or Source
Rabbit
Available Sizes
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