Phospho-Histone H2A (Ser129) polyclonal antibody

Product Specifications

Background

H2A.1 Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.

CAS Number

9007-83-4

Structure Composition

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Product Name Alternative

FLJ92027; H2A histone family; member C; H2A.1; H2A/c; H2A1; H2AFC; H2AFD; H2AFI; H2AFN; H2AFP; HIST1H2AG; HIST1H2AI; HIST1H2AK; HIST1H2AL; HIST1H2AM

Swiss Prot

P04912

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from yeast Phospho-Histone H2A (S129)

Conjugation

Unconjugated

Applications

Dilution

WB: 1/500-1/1000

Purity

Affinity Purified

Modification

Phosphorylated

Molecular Weight

Calculated MW: 14 kDa; Observed MW: 14 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

IgG

Applications Notes

Western blot analysis of Phospho-Histone H2A in Saccharomyces cerevisiae lysates treated with Methyl methanesulfonate using Phospho-Histone H2A antibody.