FOXO1 polyclonal antibody
Product Specifications
Background
Transcription factor which acts as a regulator of cell responses to oxidative stress. In the presence of KIRT1, mediates down-regulation of cyclin D1 and up-regulation of CDKN1B levels which are required for cell transition from proliferative growth to quiescence.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Product Name Alternative
FOXO1; FKHR; FOXO1A; Forkhead box protein O1; Forkhead box protein O1A; Forkhead in rhabdomyosarcoma
Swiss Prot
Q12778
Reactivity
Human, Mouse, Rat
Immunogen
A synthesized peptide derived from human FoxO1a
Conjugation
Unconjugated
Applications
WB, IHC-P, ICC/IF
Dilution
WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200
Purity
Affinity Purified
Modification
Unmodified
Molecular Weight
Calculated MW: 70 kDa; Observed MW: 70 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IgG
Applications Notes
Western blot analysis of FoxO1a in Jurkat, THP-1, SKOV-3, MCF-7 and Hela lysates using FOXO1 antibody.
Host or Source
Rabbit
Available Sizes
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