MEK1/2 polyclonal antibody
Product Specifications
Background
Dual specificity protein kinase which acts as an essential component of the MAP kinase signal transduction pathway. Binding of extracellular ligands such as growth factors, cytokines and hormones to their cell-surface receptors activates RAS and this initiates RAF1 activation. RAF1 then further activates the dual-specificity protein kinases MAP2K1/MEK1 and MAP2K2/MEK2.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Product Name Alternative
MAP2K1; MEK1; PRKMK1; Dual specificity mitogen-activated protein kinase kinase 1; MAP kinase kinase 1; MAPKK 1; MKK1; ERK activator kinase 1; MAPK/ERK kinase 1; MEK 1; MAP2K2; MEK2; MKK2; PRKMK2; Dual specificity mitogen-activated protein k
Swiss Prot
Q02750/P36507
Reactivity
Human, Mouse, Rat
Immunogen
A synthesized peptide derived from human MEK1/2
Conjugation
Unconjugated
Applications
WB, IHC-P, ICC/IF, IP
Dilution
WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20
Purity
Affinity Purified
Modification
Unmodified
Molecular Weight
Calculated MW: 43,44 kDa; Observed MW: 43,44 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IgG
Applications Notes
Western blot analysis of MEK1/2 in 293T lysates; A549 lysates using MEK1/2 antibody.
Host or Source
Rabbit
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
MP0077Q Each
Magic™ Membrane Protein Human ERBB4 (Erb-b2 receptor tyrosine kinase 4, transcript variant JM-a/CVT-2) expressed in Sf9 for Antibody Discovery
Sign In for Pricing
View Details 
bsm-33187M-APC-TR 20 µL
Alpha smooth muscle Actin Monoclonal Antibody, APC Conjugated
Sign In for Pricing
View Details 
EIA07116Bo 1 Kit
Bovine anti-G2s antibody IgG (Anti-G2s IgG) ELISA Kit
Sign In for Pricing
View Details