YY1 polyclonal antibody
Product Specifications
Background
Its activity is regulated by transcription factors and cytoplasmic proteins that have been shown to abrogate or completely inhibit YY1-mediated activation or repression. For example, it acts as a repressor in absence of adenovirus E1A protein but as an activator in its presence. Acts synergistically with the SMAD1 and SMAD4 in bone morphogenetic protein (BMP) -mediated cardiac-specific gene expression.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Product Name Alternative
YY1; Delta transcription factor; INO80 complex subunit S; NF-E1; Yin and yang 1; YY-1
Swiss Prot
P25490
Reactivity
Human, Mouse, Rat
Immunogen
A synthesized peptide derived from human YY1
Conjugation
Unconjugated
Applications
WB, IHC-P, ICC/IF, IP
Dilution
WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20
Purity
Affinity Purified
Modification
Unmodified
Molecular Weight
Calculated MW: 45 kDa; Observed MW: 68 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IgG
Applications Notes
Western blot analysis of YY1 in HeLa lysates; Daudi lysates using YY1 antibody.
Host or Source
Rabbit
Available Sizes
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