Melatonin Receptor 1A polyclonal antibody
Product Specifications
Background
This gene encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This receptor is a G-protein coupled, 7-transmembrane receptor that is responsible for melatonin effects on mammalian circadian rhythm and reproductive alterations affected by day length. The receptor is an integral membrane protein that is readily detectable and localized to two specific regions of the brain. The hypothalamic suprachiasmatic nucleus appears to be involved in circadian rhythm while the hypophysial pars tuberalis may be responsible for the reproductive effects of melatonin.
CAS Number
9007-83-4
Structure Composition
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Product Name Alternative
MTNR1A; Melatonin receptor type 1A; Mel-1A-R; Mel1a receptor
Swiss Prot
P48039
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide of human MTR1A. AA range:191-240
Conjugation
Unconjugated
Applications
ICC/IF, ELISA
Dilution
IF: 1/50-1/200 ELISA: 1/10000
Purity
Affinity Purified
Modification
Unmodified
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IgG
Applications Notes
Immunofluorescence analysis of Melatonin Receptor 1A in HepG2 cells using Melatonin Receptor 1A antibody. Sample with blocking peptide on the right.
Host or Source
Rabbit
Available Sizes
Curated Selection
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