What is the catalog number for Phospho-IKK beta (Tyr188) polyclonal antibody?

The catalog number for Phospho-IKK beta (Tyr188) polyclonal antibody is BZ16477.

What sizes are available for Phospho-IKK beta (Tyr188) polyclonal antibody?

Phospho-IKK beta (Tyr188) polyclonal antibody is available in the following size(s): 50 µL, 100 µL.

How many pack sizes does Phospho-IKK beta (Tyr188) polyclonal antibody come in?

Phospho-IKK beta (Tyr188) polyclonal antibody is available in 2 different pack sizes.

Is Phospho-IKK beta (Tyr188) polyclonal antibody in stock?

Phospho-IKK beta (Tyr188) polyclonal antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Phospho-IKK beta (Tyr188) polyclonal antibody

Product Specifications

Background

The NF-κB/Rel transcription factors are present in the cytosol in an inactive state, complexed with the inhibitory IκB proteins (1-3) . Most agents that activate NF-κB do so through a common pathway based on phosphorylation-induced, proteasome-mediated degradation of IκB (3-7) . The key regulatory step in this pathway involves activation of a high molecular weight IκB kinase (IKK) complex whose catalysis is generally carried out by three tightly associated IKK subunits.

CAS Number

9007-83-4

Structure Composition

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Product Name Alternative

IKBKB; IKKB; Inhibitor of nuclear factor kappa-B kinase subunit beta; I-kappa-B-kinase beta; IKK-B; IKK-beta; IkBKB; I-kappa-B kinase 2; IKK2; Nuclear factor NF-kappa-B inhibitor kinase beta; NFKBIKB

Swiss Prot

O14920

Reactivity

Human, Mouse, Rat, Monkey

Immunogen

The antiserum was produced against synthesized peptide derived from human IKK-beta around the phosphorylation site of Tyr188. AA range:161-210

Conjugation

Unconjugated

Applications

WB, IHC-P, ELISA

Dilution

WB: 1/500-1/1000 IHC: 1/50-1/100 ELISA: 1/10000

Purity

Affinity Purified

Modification

Phosphorylated

Molecular Weight

Calculated MW: 87 kDa; Observed MW: 87 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

IgG

Applications Notes

Immunohistochemistry analysis of paraffin-embedded Human breast cancer using Phospho-IKK beta antibody.High-pressure and temperature Tris-EDTA pH 8.0 was used for antigen retrieval.Sample with blocking peptide on the right.