Cleaved-Caspase 6 p18 polyclonal antibody
Product Specifications
Background
Caspase-6 (Mch2) is one of the major executioner caspases functioning in cellular apoptotic processes. Upon apoptotic stimulation, initiator caspases such as caspase-9 are cleaved and activated. The activated upstream caspases further process downstream executioner caspases, such as caspase-3 and caspase-6, by cleaving them into large and small subunits, thereby initiating a caspase cascade leading to apoptosis. One of the major targets for caspase-6 is the membrane associated protein lamin A.
CAS Number
9007-83-4
Structure Composition
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Product Name Alternative
CASP6; MCH2; Caspase-6; CASP-6; Apoptotic protease Mch-2
Swiss Prot
P55212
Reactivity
Human, Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human Caspase 6. AA range:130-179
Conjugation
Unconjugated
Applications
WB, IHC-P, ELISA
Dilution
WB: 1/500-1/1000 IHC: 1/50-1/100 ELISA: 1/10000
Purity
Affinity Purified
Modification
Cleaved
Molecular Weight
Calculated MW: 33 kDa; Observed MW: 20,35 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IgG
Applications Notes
Western blot analysis of Cleaved-Caspase 6 p18 in various lysates using Cleaved-Caspase 6 p18 antibody.
Host or Source
Rabbit
Available Sizes
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