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Phospho-YAP (Ser127) polyclonal antibody

Product Specifications

Background

YAP (Yes-associated protein, YAP65) was identified based on its ability to associate with the SH3 domain of Yes. Transcriptional regulator which can act both as a coactivator and a corepressor and is the critical downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis.

CAS Number

9007-83-4

Structure Composition

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Product Name Alternative

YAP1; YAP65; Yorkie homolog; 65 kDa Yes-associated protein; YAP65

Swiss Prot

P46937

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide of human YAP1

Conjugation

Unconjugated

Applications

WB, IHC-P, ICC/IF

Dilution

WB: 1/500-1/1000 IHC: 1/50-1/100 ICC: 1/100-1/200

Purity

Affinity Purified

Modification

Phosphorylated

Molecular Weight

Calculated MW: 54 kDa; Observed MW: 65 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

IgG

Applications Notes

Western blot analysis of Phospho-YAP in COS7 lysates using Phospho-YAP antibody.

Host or Source

Rabbit

Available Sizes

Frequently Asked Questions

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