Phospho-mTOR (Thr2446) polyclonal antibody
Product Specifications
Background
An atypical kinase belonging to the PIKK family of kinases. Controls cell growth through protein synthesis regulation. Downstream of PI3K/Akt pathway and required for cell survival. Acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex.
CAS Number
9007-83-4
Structure Composition
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Product Name Alternative
MTOR; FRAP; FRAP1; FRAP2; RAFT1; RAPT1; Serine/threonine-protein kinase mTOR; FK506-binding protein 12-rapamycin complex-associated protein 1; FKBP12-rapamycin complex-associated protein; Mammalian target of rapamycin; mTOR; Mechanistic tar
Swiss Prot
P42345
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide of human MTOR
Conjugation
Unconjugated
Applications
WB
Dilution
WB: 1/500-1/1000
Purity
Affinity Purified
Modification
Phosphorylated
Molecular Weight
Calculated MW: 289 kDa; Observed MW: 220 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IgG
Applications Notes
Western blot analysis of Phospho-mTOR in 3T3 lysates using Phospho-mTOR antibody.
Host or Source
Rabbit
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
![Tau (MAPT) Mouse Monoclonal Antibody [Clone ID: OTI8G7]](https://cdn.genprice.uk/products/937/6868c420994c49e6dc4079be/imageurl/ta815394.webp)
C2395-13F1-PE 100 µL
CD42b (CD42b Antigen, CD42b alpha, Antigen CD42b alpha, BSS, Glycocalicin, Glycoprotein Ib (Platelet) alpha Polypeptide, Glycoprotein Ib alpha, GP-Ib alpha, GPIb-alpha, GPIbA, GP1BA, MGC34595, Platelet Glycoprotein Ib alpha Chain, Platelet Glycoprotein Ib alpha Polypeptide, Platelet Membrane Glycoprotein 1b alpha Subunit) (PE) discontinued
Ask
View Details 
GTR15199102 1 Vial
Lentiviral mouse Smim18 shRNA (UAS) - Lentiviral mouse Smim18 shRNA (UAS, GFP) plasmid
Ask
View Details