Phospho-mTOR (Thr2446) polyclonal antibody
Product Specifications
Background
An atypical kinase belonging to the PIKK family of kinases. Controls cell growth through protein synthesis regulation. Downstream of PI3K/Akt pathway and required for cell survival. Acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex.
CAS Number
9007-83-4
Structure Composition
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Product Name Alternative
MTOR; FRAP; FRAP1; FRAP2; RAFT1; RAPT1; Serine/threonine-protein kinase mTOR; FK506-binding protein 12-rapamycin complex-associated protein 1; FKBP12-rapamycin complex-associated protein; Mammalian target of rapamycin; mTOR; Mechanistic tar
Swiss Prot
P42345
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide of human MTOR
Conjugation
Unconjugated
Applications
WB
Dilution
WB: 1/500-1/1000
Purity
Affinity Purified
Modification
Phosphorylated
Molecular Weight
Calculated MW: 289 kDa; Observed MW: 220 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IgG
Applications Notes
Western blot analysis of Phospho-mTOR in 3T3 lysates using Phospho-mTOR antibody.
Host or Source
Rabbit
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
K1753005 3x 1.0 µg
PTMAP3 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Human)
Sign In for Pricing
View Details 
MBS7067660 Inquire
Recombinant Salmonella agona Undecaprenyl-diphosphatase (uppP), partial
Sign In for Pricing
View Details GTR15152270 1 Vial
Lentiviral human C2CD5 shRNA (UAS) - Lentiviral human C2CD5 shRNA (UAS, iRFP) (25)
Sign In for Pricing
View Details 
orb1736633-01 48 Tests
Pig Platelet Derived Growth Factor BB (PDGFBB) ELISA Kit
Sign In for Pricing
View Details orb1736633-02 96 Tests
Pig Platelet Derived Growth Factor BB (PDGFBB) ELISA Kit
Sign In for Pricing
View Details