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Phospho-FRS2 (Tyr436) polyclonal antibody

Product Specifications

Background

Adapter protein that links FGR and NGF receptors to downstream signaling pathways. Involved in the activation of MAP kinases. Modulates signaling via SHC1 by competing for a common binding site on NTRK1.

CAS Number

9007-83-4

Structure Composition

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Product Name Alternative

Fibroblast growth factor receptor substrate 2; FGFR substrate 2; FGFR-signaling adaptor SNT; Suc1-associated neurotrophic factor target 1; SNT-1

Swiss Prot

Q8WU20

Reactivity

Human

Immunogen

Synthetic peptide of human FRS2

Conjugation

Unconjugated

Applications

WB, IHC-P

Dilution

WB: 1/500-1/1000 IHC: 1/50-1/100

Purity

Affinity Purified

Modification

Phosphorylated

Molecular Weight

Calculated MW: 57 kDa; Observed MW: 65 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

IgG

Applications Notes

Western blot analysis of Phospho-FRS2 in HUVEC lysates using Phospho-FRS2 antibody.

Host or Source

Rabbit

Available Sizes

Frequently Asked Questions

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