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Phospho-PYK2 (Tyr402) polyclonal antibody

Product Specifications

Background

PYK2 a nonreceptor tyrosine kinase of the Fak family. Predominantly expressed in the cells derived from hematopoietic lineages and in the central nervous system. PYK2 is one of the signaling mediators for G-protein-coupled receptors. Involved in calcium induced regulation of ion channel and activation of the map kinase signaling pathway. Interacts with the SH2 domain of Grb2.

CAS Number

9007-83-4

Structure Composition

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Product Name Alternative

PTK2B; FAK2; PYK2; RAFTK; Protein-tyrosine kinase 2-beta; Calcium-dependent tyrosine kinase; CADTK; Calcium-regulated non-receptor proline-rich tyrosine kinase; Cell adhesion kinase beta; CAK-beta; CAKB; Focal adhesion kinase 2; FADK 2; Pro

Swiss Prot

Q14289

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide of human PTK2B

Conjugation

Unconjugated

Applications

WB, IHC-P, ICC/IF

Dilution

WB: 1/500-1/1000 IHC: 1/50-1/100 ICC: 1/100-1/200

Purity

Affinity Purified

Modification

Phosphorylated

Molecular Weight

Calculated MW: 116 kDa; Observed MW: 116 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

IgG

Applications Notes

Western blot analysis of Phospho-PYK2 in 293 lysates using Phospho-PYK2 antibody.

Host or Source

Rabbit

Available Sizes

Curated Selection

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