Phospho-LIM Kinase 1 (Thr508) polyclonal antibody
Product Specifications
Background
Protein kinase which regulates actin filament dynamics. Phosphorylates and inactivates the actin binding/depolymerizing factor cofilin, thereby stabilizing the actin cytoskeleton. Stimulates axonal outgrowth and may be involved in brain development. Isoform 3 has a dominant negative effect on actin cytoskeletal changes.
CAS Number
9007-83-4
Structure Composition
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Product Name Alternative
LIMK1; LIMK; LIM domain kinase 1; LIMK-1
Swiss Prot
P53667
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide of human LIMK1
Conjugation
Unconjugated
Applications
WB, IHC-P, ICC/IF
Dilution
WB: 1/500-1/1000 IHC: 1/50-1/100 ICC: 1/100-1/200
Purity
Affinity Purified
Modification
Phosphorylated
Molecular Weight
Calculated MW: 73 kDa; Observed MW: 73 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IgG
Applications Notes
Western blot analysis of Phospho-LIM Kinase 1 in C2C12, Hela, 293 lysates using Phospho-LIM Kinase 1 antibody.
Host or Source
Rabbit
Available Sizes
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