Phospho-PDPK1 (Ser241) polyclonal antibody
Product Specifications
Background
Phosphoinositide-dependent protein kinase 1 (PDK1) plays a central role in many signal transduction pathways including the activation of Akt and the PKC isoenzymes p70 S6 kinase and RSK. Through its effects on these kinases, PDK1 is involved in the regulation of a wide variety of processes, including cell proliferation, differentiation and apoptosis.
CAS Number
9007-83-4
Structure Composition
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Product Name Alternative
PDPK1; PDK1; 3-phosphoinositide-dependent protein kinase 1; hPDK1
Swiss Prot
O15530
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide of human PDPK1
Conjugation
Unconjugated
Applications
WB, IHC-P, ICC/IF
Dilution
WB: 1/500-1/1000 IHC: 1/50-1/100 ICC: 1/100-1/200
Purity
Affinity Purified
Modification
Phosphorylated
Molecular Weight
Calculated MW: 63 kDa; Observed MW: 63 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IgG
Applications Notes
Western blot analysis of Phospho-PDPK1 in 293, PC-12 lysates using Phospho-PDPK1 antibody.
Host or Source
Rabbit
Available Sizes
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