SOD2 polyclonal antibody
Product Specifications
Background
SOD-2 is a homotetrameric manganese enzyme (also known as MnSOD) that functions in the mitochondrion. ROS are implicated in a wide range of degenerative processes, including Alzheimer’s disease, Parkinson’s disease and ischemic heart disease. Homozygous mutant mice, which lack SOD-2, exhibit dilated cardiomyopathy, accumulation of lipid in liver and skeletal muscle, metabolic acidosis, oxidative DNA damage and respiratory chain deficiencies in heart and skeletal muscle.
CAS Number
9007-83-4
Structure Composition
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Product Name Alternative
IPOB; IPO-B; MNSOD; MVCD6; Mn-SOD; SOD2
Swiss Prot
P04179
Reactivity
Human, Mouse, Rat, Monkey
Immunogen
Synthetic peptide.
Conjugation
Unconjugated
Applications
WB
Dilution
WB: 1/500-1/1000
Purity
Affinity Purified
Modification
Unmodified
Molecular Weight
Calculated MW: 25 kDa; Observed MW: 25 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IgG
Applications Notes
Western blot analysis of SOD2 in 293, COS7, C6, 3T3 and Hela lysates using SOD2 antibody.
Host or Source
Rabbit
Available Sizes
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