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Smad1/5/9 polyclonal antibody

Product Specifications

Background

Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD1 is a receptor-regulated SMAD (R-SMAD) . SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1. May act synergistically with SMAD4 and YY1 in bone morphogenetic protein (BMP) -mediated cardiac-specific gene expression.

CAS Number

9007-83-4

Structure Composition

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Product Name Alternative

Mothers against decapentaplegic homolog 1/5/9; MAD homolog 1; Mothers against DPP homolog 1; JV4-1; Mad-related protein 1; SMAD family member 1; SMAD 1/5/9; Smad1; hSMAD1; Transforming growth factor-beta-signaling protein 1; BSP-1

Swiss Prot

Q15797/Q99717/O15198

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from human Smad1/5/9. at AA range: 291-340

Conjugation

Unconjugated

Applications

WB, ELISA

Dilution

WB: 1/500-1/1000 ELISA: 1/10000

Purity

Affinity Purified

Modification

Unmodified

Molecular Weight

Calculated MW: 52 kDa; Observed MW: 52 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

IgG

Applications Notes

Western blot analysis of Smad1/5/9 in 293T lysates using Smad1/5/9 antibody.

Host or Source

Rabbit

Available Sizes

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