FOXA polyclonal antibody
Product Specifications
Background
Forkhead box protein A1 is a transcription factor required for the development of endoderm-derived organs, such as liver, lung, and prostate. FoxA1 functions as a pioneer factor that is recruited primarily to the distant enhancers to change chromatin structure for transcription in a cell type-specific manner. Involved in regulation of apoptosis by inhibiting the expression of BCL2. Involved in cell cycle regulation by activating expression of CDKN1B, alone or in conjunction with BRCA1.
CAS Number
9007-83-4
Structure Composition
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Product Name Alternative
FOXA1; Forkhead box A1; Forkhead box protein A1; HNF-3-alpha; TCF3A; HNF3A; Transcription factor 3A
Swiss Prot
P55317
Reactivity
Human, Mouse, Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human FOXA1 around the non-acetylation site of Lys265. AA range:231-280
Conjugation
Unconjugated
Applications
WB, ELISA
Dilution
WB: 1/500-1/1000 ELISA: 1/10000
Purity
Affinity Purified
Modification
Unmodified
Molecular Weight
Calculated MW: 49 kDa; Observed MW: 49 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IgG
Applications Notes
Western blot analysis of FOXA in A549 lysates using FOXA antibody.
Host or Source
Rabbit
Available Sizes
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