FOXA polyclonal antibody

Product Specifications

Background

Forkhead box protein A1 is a transcription factor required for the development of endoderm-derived organs, such as liver, lung, and prostate. FoxA1 functions as a pioneer factor that is recruited primarily to the distant enhancers to change chromatin structure for transcription in a cell type-specific manner. Involved in regulation of apoptosis by inhibiting the expression of BCL2. Involved in cell cycle regulation by activating expression of CDKN1B, alone or in conjunction with BRCA1.

CAS Number

9007-83-4

Structure Composition

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Product Name Alternative

FOXA1; Forkhead box A1; Forkhead box protein A1; HNF-3-alpha; TCF3A; HNF3A; Transcription factor 3A

Swiss Prot

P55317

Reactivity

Human, Mouse, Rat

Immunogen

The antiserum was produced against synthesized peptide derived from human FOXA1 around the non-acetylation site of Lys265. AA range:231-280

Conjugation

Unconjugated

Applications

WB, ELISA

Dilution

WB: 1/500-1/1000 ELISA: 1/10000

Purity

Affinity Purified

Modification

Unmodified

Molecular Weight

Calculated MW: 49 kDa; Observed MW: 49 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

IgG

Applications Notes

Western blot analysis of FOXA in A549 lysates using FOXA antibody.

Host or Source

Rabbit

Available Sizes

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