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PSPN polyclonal antibody

Product Specifications

Background

The protein encoded by this gene is a neurotrophic factor, belonging to the GDNF family. Neurotrophic factors are important for the proper development and maintenance of the nervous system. These factors promote neuronal survival and can prevent the neuronal degeneration associated with injury, toxin exposure, or neurodegenerative disease. The encoded protein has amino acid similarity to its other family members, glial cell line-derived neurotrophic factor and neurturin. This gene product promotes the survival of ventral midbrain dopaminergic neurons in culture and prevents their degeneration after 6-hydroxydopamine treatment in vivo.

CAS Number

9007-83-4

Structure Composition

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Product Name Alternative

PSPN; Persephin; PSP

Swiss Prot

O60542

Reactivity

Human

Immunogen

The antiserum was produced against synthesized peptide derived from the C-terminal region of human PSPN. AA range:101-150

Conjugation

Unconjugated

Applications

WB, ELISA

Dilution

WB: 1/500-1/1000 ELISA: 1/10000

Purity

Affinity Purified

Modification

Unmodified

Molecular Weight

Calculated MW: 17 kDa; Observed MW: 17 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

IgG

Applications Notes

Western blot analysis of PSPN in 293 lysates using PSPN antibody.

Host or Source

Rabbit

Available Sizes

Curated Selection

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