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SIRP alpha/beta polyclonal antibody

Product Specifications

Background

Immunoglobulin-like cell surface receptor for CD47. Acts as docking protein and induces translocation of PTPN6, PTPN11 and other binding partners from the cytosol to the plasma membrane. Supports adhesion of cerebellar neurons, neurite outgrowth and glial cell attachment.

CAS Number

9007-83-4

Structure Composition

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Product Name Alternative

SIRPA; BIT; MFR; MYD1; PTPNS1; SHPS1; SIRP; Tyrosine-protein phosphatase non-receptor type substrate 1; SHP substrate 1; SHPS-1; Brain Ig-like molecule with tyrosine-based activation motifs; Bit; CD172 antigen-like family member A; CD172a; SIRPB1; Signal-regulatory protein beta-1 isoform 3; SIRP-beta-1 isoform 3

Swiss Prot

P78324/Q5TFQ8

Reactivity

Human

Immunogen

The antiserum was produced against synthesized peptide derived from the Internal region of human SIRPA/SIRPB1. AA range:281-330

Conjugation

Unconjugated

Applications

WB, IHC-P, ELISA

Dilution

WB: 1/500-1/1000 IHC: 1/50-1/100 ELISA: 1/10000

Purity

Affinity Purified

Modification

Unmodified

Molecular Weight

Calculated MW: 55 kDa; Observed MW: 55 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

IgG

Applications Notes

Western blot analysis of SIRP alpha/beta in Hela lysates using SIRP alpha/beta antibody.

Host or Source

Rabbit

Available Sizes

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