IL-18 Receptor Accessory Protein polyclonal antibody

Product Specifications

Background

Interleukin 18 receptor accessory protein, also known as IL18RAP and CDw218b (cluster of differentiationw218b), is a human gene. The protein encoded by this gene is an accessory subunit of the heterodimeric receptor for IL18. This protein enhances the IL18 binding activity of IL18R1 (IL1RRP), a ligand binding subunit of IL18 receptor. The coexpression of IL18R1 and this protein is required for the activation of NF-κB and MAPK8 (JNK) in response to IL18.

CAS Number

9007-83-4

Structure Composition

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Product Name Alternative

IL-18 Receptor Accessory Protein; ACPL; CD218b; IL18RB; CDw218b

Swiss Prot

O95256

Reactivity

Human

Immunogen

Synthetic peptide from human protein at AA range: 291-340

Conjugation

Unconjugated

Applications

IHC-P, ELISA

Dilution

IHC: 1/50-1/100 ELISA: 1/10000

Purity

Affinity Purified

Modification

Unmodified

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

IgG

Applications Notes

Immunohistochemistry analysis of paraffin-embedded Human kidney using IL-18 Receptor Accessory Protein antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.