Angiopoietin 1 polyclonal antibody
Product Specifications
Background
Binds and activates TEK/TIE2 receptor by inducing its dimerization and tyrosine phosphorylation. Plays an important role in the regulation of angiogenesis, endothelial cell survival, proliferation, migration, adhesion and cell spreading, reorganization of the actin cytoskeleton, but also maintenance of vascular quiescence. Required for normal angiogenesis and heart development during embryogenesis. After birth, activates or inhibits angiogenesis, depending on the context.
CAS Number
9007-83-4
Structure Composition
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Product Name Alternative
ANGPT1; KIAA0003; Angiopoietin-1; ANG-1
Swiss Prot
Q15389
Reactivity
Human, Rat
Immunogen
The antiserum was produced against synthesized peptide derived from the N-terminal region of human ANGPT1. AA range:1-50
Conjugation
Unconjugated
Applications
WB, IHC-P, ELISA
Dilution
WB: 1/500-1/1000 IHC: 1/50-1/100 ELISA: 1/10000
Purity
Affinity Purified
Modification
Unmodified
Molecular Weight
Calculated MW: 58 kDa; Observed MW: 58 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IgG
Applications Notes
Western blot analysis of Angiopoietin 1 in A549, K562 lysates using Angiopoietin 1 antibody.
Host or Source
Rabbit
Available Sizes
Curated Selection
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