TLE1/2/3/4 polyclonal antibody
Product Specifications
Background
Transcriptional corepressor that binds to a number of transcription factors. Inhibits NF-kappa-B-regulated gene expression. Inhibits the transcriptional activation mediated by FOXA2, and by CTNNB1 and TCF family members in Wnt signaling.
CAS Number
9007-83-4
Structure Composition
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
TLE1; Transducin-like enhancer protein 1; E (Sp1) homolog; Enhancer of split groucho-like protein 1; ESG1; TLE2; Transducin-like enhancer protein 2; Enhancer of split groucho-like protein 2; ESG2; TLE3; KIAA1547; Transducin-like enhancer protein 3; Enhance
Swiss Prot
Q04724/Q04725/Q04726/Q04727
Reactivity
Human, Mouse, Rat
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human TLE1/2/3/4.
Conjugation
Unconjugated
Applications
WB
Dilution
WB: 1/500-1/2000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodified
Molecular Weight
~ 82 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
TLE1/2/3/4 polyclonal antibody detects endogenous levels of TLE1/2/3/4 protein.
Applications Notes
Western blot analysis of TLE1/2/3/4 expression in A549 (A), K562 (B), Hela (C), NIH3T3 (D), mouse liver (E) whole cell lysates.
Host or Source
Rabbit
Available Sizes
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