PPAR delta (4G5) monoclonal antibody
Product Specifications
Background
Ligand-activated transcription factor. Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Has a preference for poly-unsaturated fatty acids, such as gamma-linoleic acid and eicosapentanoic acid. Once activated by a ligand, the receptor binds to promoter elements of target genes. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the acyl-CoA oxidase gene. Decreases expression of NPC1L1 once activated by a ligand.
CAS Number
9007-83-4
Structure Composition
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Product Name Alternative
FAAR; NR1C2; NUC1; Peroxisome proliferative activated receptor delta
Swiss Prot
Q03181
Reactivity
Human, Rat, Mouse
Immunogen
Purified recombinant protein expressed in E.coli.
Conjugation
Unconjugated
Applications
WB, IHC-P
Dilution
WB: 1/500-1/1000 IHC: 1/50-1/100
Purity
Affinity Purified
Modification
Unmodified
Molecular Weight
Calculated MW: 50 kDa; Observed MW: 50 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IgG1
Applications Notes
Immunohistochemistry analysis of paraffin-embedded Human Brain Tissue using PPAR delta antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
Host or Source
Mouse
Available Sizes
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