ERK1 (1D10) monoclonal antibody

Product Specifications

Background

Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade. They participate also in a signaling cascade initiated by activated KIT and KITLG/SCF. Depending on the cellular context, the MAPK/ERK cascade mediates diverse biological functions such as cell growth, adhesion, survival and differentiation through the regulation of transcription, translation, cytoskeletal rearrangements.

CAS Number

9007-83-4

Structure Composition

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Product Name Alternative

MAPK3

Swiss Prot

P27361

Reactivity

Human, Rat, Mouse

Immunogen

Purified recombinant protein expressed in E.coli.

Conjugation

Unconjugated

Applications

IHC-P

Dilution

IHC: 1/50-1/100

Purity

Affinity Purified

Modification

Unmodified

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

IgG1

Applications Notes

Immunohistochemistry analysis of paraffin-embedded Human Tonsil Tissue using ERK1 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.