SGK1 (6E4) monoclonal antibody
Product Specifications
Background
Serum and glucocorticoid-inducible kinase (SGK) is a serine/threonine kinase closely related to Akt. SGK is rapidly induced in response to a variety of stimuli, including serum, glucocorticoid, follicle stimulating hormone, osmotic shock, and mineralocorticoids. SGK activation can be accomplished via HGF PI3K-dependent pathways and by integrin-mediated PI3K-independent pathways. Induction and activation of SGK has been implicated in activating the modulation of anti-apoptotic and cell cycle regulation.
CAS Number
9007-83-4
Structure Composition
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Product Name Alternative
SGK1; SGK; Serine/threonine-protein kinase Sgk1; Serum/glucocorticoid-regulated kinase 1
Swiss Prot
O00141
Reactivity
Human, Rat, Mouse
Immunogen
Synthetic peptide conjugated to KLH.
Conjugation
Unconjugated
Applications
IHC-P
Dilution
IHC: 1/50-1/100
Purity
Affinity Purified
Modification
Unmodified
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IgG1
Applications Notes
Immunohistochemistry analysis of paraffin-embedded Human Brain Tissue using SGK1 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
Host or Source
Mouse
Available Sizes
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