Phospho-CaMKII (Thr287) (4A8) monoclonal antibody

Product Specifications

Background

CaM-kinase II (CAMK2) is a prominent kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Member of the NMDAR signaling complex in excitatory synapses it may regulate NMDAR-dependent potentiation of the AMPAR and synaptic plasticity.

CAS Number

9007-83-4

Structure Composition

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Product Name Alternative

Calcium/calmodulin dependent protein kinase II; KCC2A

Swiss Prot

Q13554/Q13555/Q13557

Reactivity

Human, Rat, Mouse

Immunogen

Synthetic peptide conjugated to KLH.

Conjugation

Unconjugated

Applications

IHC-P

Dilution

IHC: 1/50-1/100

Purity

Affinity Purified

Modification

Phosphorylated

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

IgG1

Applications Notes

Immunohistochemistry analysis of paraffin-embedded rat Brain Tissue using Phospho-CaMKII antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.