ABCB5 (8D2) monoclonal antibody
Product Specifications
Background
Drug efflux transporter present in a number of stem cells that acts as a regulator of cellular differentiation. Able to mediate efflux from cells of the rhodamine dye and of the therapeutic drug doxorubicin. Specifically present in limbal stem cells, where it plays a key role in corneal development and repair.
CAS Number
9007-83-4
Structure Composition
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Product Name Alternative
ABCB5 P-gp; ATP binding cassette sub family B (MDR/TAP) member 5; P glycoprotein ABCB5
Swiss Prot
Q2M3G0
Reactivity
Human
Immunogen
Synthetic Peptide of ABCB5
Conjugation
Unconjugated
Applications
WB, ICC/IF
Dilution
WB: 1/500-1/1000 IF: 1/50-1/200
Purity
Affinity Purified
Modification
Unmodified
Molecular Weight
Calculated MW: 139 kDa; Observed MW: 90 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IgG1
Applications Notes
Western blot analysis of ABCB5 in K562 lysates using ABCB5 antibody.
Host or Source
Mouse
Available Sizes
Curated Selection
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