Prohibitin (5H7) monoclonal antibody
Product Specifications
Background
PHB1 is 30kDa tumor suppressor protein involved in cell cycle control. PHB1 has been found in mitochondria, the nucleus and the plasma membrane, as well as extracellularly in circulation. In mitochondria prohibitins mainly exist as membrane-bound ring complexes and function as chaperones maintaining mitochondrial protein stability during protein synthesis and transportation.
CAS Number
9007-83-4
Structure Composition
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Product Name Alternative
PHB1; HEL-215; HEL-S-54e
Swiss Prot
P35232
Reactivity
Human, Mouse, Rat, Monkey
Immunogen
Purified recombinant fragment of human PHB expressed in E. Coli.
Conjugation
Unconjugated
Applications
WB, IHC-P, ICC/IF, FC
Dilution
WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 FC: 1/50-1/100
Purity
Affinity Purified
Modification
Unmodified
Molecular Weight
Calculated MW: 30 kDa; Observed MW: 30 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IgG1
Applications Notes
Western blot analysis of Prohibitin in C6, COS7, 3T3 and Hela lysates using Prohibitin antibody.
Host or Source
Mouse
Available Sizes
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