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Prohibitin (5H7) monoclonal antibody

Product Specifications

Background

PHB1 is 30kDa tumor suppressor protein involved in cell cycle control. PHB1 has been found in mitochondria, the nucleus and the plasma membrane, as well as extracellularly in circulation. In mitochondria prohibitins mainly exist as membrane-bound ring complexes and function as chaperones maintaining mitochondrial protein stability during protein synthesis and transportation.

CAS Number

9007-83-4

Structure Composition

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Product Name Alternative

PHB1; HEL-215; HEL-S-54e

Swiss Prot

P35232

Reactivity

Human, Mouse, Rat, Monkey

Immunogen

Purified recombinant fragment of human PHB expressed in E. Coli.

Conjugation

Unconjugated

Applications

WB, IHC-P, ICC/IF, FC

Dilution

WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 FC: 1/50-1/100

Purity

Affinity Purified

Modification

Unmodified

Molecular Weight

Calculated MW: 30 kDa; Observed MW: 30 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

IgG1

Applications Notes

Western blot analysis of Prohibitin in C6, COS7, 3T3 and Hela lysates using Prohibitin antibody.

Host or Source

Mouse

Available Sizes

Frequently Asked Questions

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