BAG1 (2C12) monoclonal antibody

Product Specifications

Background

Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release.Inhibits the pro-apoptotic function of PPP1R15A, and has anti-apoptotic activity.Markedly increases the anti-cell death function of BCL2 induced by various stimuli.

CAS Number

9007-83-4

Structure Composition

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Product Name Alternative

BAG1; HAP; BAG family molecular chaperone regulator 1; BAG-1; Bcl-2-associated athanogene 1

Swiss Prot

Q99933

Reactivity

Transfected

Immunogen

Purified recombinant human Bag1 protein fragments expressed in E.coli.

Conjugation

Unconjugated

Applications

Dilution

WB: 1/500-1/1000

Purity

Affinity Purified

Modification

Unmodified

Molecular Weight

Calculated MW: 39 kDa; Observed MW: 52,46,33 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

IgG1

Applications Notes

Western blot analysis of BAG1 in CHO-K1 , transfected with a Human pEGFPC1BAG1 construct or transfected with a Human pEGFPC1 construct , using Bag1 antibody.