GADD45A (6C3) monoclonal antibody
Product Specifications
Background
This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The DNA damage-induced transcription of this gene is mediated by both p53-dependent and -independent mechanisms. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
CAS Number
9007-83-4
Structure Composition
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Product Name Alternative
DDIT1; GADD45
Swiss Prot
P24522
Reactivity
Transfected
Immunogen
Purified recombinant human GADD45 α protein expressed in E.coli
Conjugation
Unconjugated
Applications
WB
Dilution
WB: 1/500-1/1000
Purity
Affinity Purified
Modification
Unmodified
Molecular Weight
Calculated MW: 18 kDa; Observed MW: 22 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IgG1
Applications Notes
Western blot analysis of GADD45 alpha in CHO-K1 lysatesand CHO-K1 transfected by GADD45 alpha His fusion protein lysates using GADD45 alpha antibody.
Host or Source
Mouse
Available Sizes
Curated Selection
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