FOXP3 (7H9) monoclonal antibody
Product Specifications
Background
Defects in FOXP3 are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) [MIM:304790]; also known as X-linked autoimmunity-immunodeficiency syndrome. IPEX is characterized by neonatal onset insulin-dependent diabetes mellitus, infections, secretory diarrhea, trombocytopenia, anemia and eczema. It is usually lethal in infancy.
CAS Number
9007-83-4
Structure Composition
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Product Name Alternative
FOXP3; IPEX; JM2; Forkhead box protein P3; Scurfin
Swiss Prot
Q9BZS1
Reactivity
Transfected
Immunogen
Purified recombinant human FOXP3 protein fragments expressed in E.coli.
Conjugation
Unconjugated
Applications
WB, ICC/IF
Dilution
WB: 1/500-1/1000 IF: 1/50-1/200
Purity
Affinity Purified
Modification
Unmodified
Molecular Weight
Calculated MW: 47 kDa; Observed MW: 47 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IgG1
Applications Notes
Western blot analysis of FOXP3 in CHO-K1 lysates and CHO-K1 transfected by FOXP3 lysates using FOXP3 antibody.
Host or Source
Mouse
Available Sizes
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