PFKFB1 (E442) polyclonal antibody
Product Specifications
Background
PFK-1 undergoes activation in the presence of elevated AMP. The most potent activator is fructose-2,6-bisphosphate, which is produced by PFK-2 from the same substrate, fructose 6-phosphate. PFK-2 is bifunctional and a key regulator for PFK-1. PFK-2 catalyzes the synthesis of fructose-2,6-bisphosphate, and contains fructose-2,6-biphosphatase activity that catalyzes the degradation of fructose-2,6-bisphosphate. PFK-2 is dimeric and isoenzymes include PFK-2 liver (PFKFB1, PFRX), PFK-2 cardiac (PFKFB2), PFK-2 placental (PFKFB3, inducible PFK-2) and PFK-2 testis (PFKFB4) .
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
PFK-2 liver; PFKFB1; PFRX; F6PK; 6PF-2-K/Fru-2; 6-P2ASE liver isozyme; 6-phosphofructo-2-kinase/fructose-2; 6-biphosphatase 1
Swiss Prot
P16118
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding to amino acids 410-460 of Human PFKFB1.
Conjugation
Unconjugated
Applications
WB IHC
Dilution
WB: 1:500~1:1000 IHC: 1:50~1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodified
Molecular Weight
~ 55 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
PFKFB1 (E442) polyclonal antibody detects endogenous levels of PFKFB1 protein.
Applications Notes
Western blot (WB) analysis of PFKFB1 (E442) polyclonal antibody in extracts from hela cells.
Host or Source
Rabbit
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
E45H01681-2 20 µg
TRAF4AF1 (KNSTRN) (NM_001142762) Human Over-expression Lysate
Sign In for Pricing
View Details orb1607153 100 µL
Phospho-GSK-3 Beta (Ser9) Mouse Monoclonal Antibody (AP)
Sign In for Pricing
View Details 
243461-FITC 100 µL
ARHGEF10 (Rho Guanine Nucleotide Exchange Factor (GEF) 10, DKFZp686H0726, GEF10, MGC131664) (FITC)
Sign In for Pricing
View Details 221099-01 50 µL
BRCA1, phosphorylated (S1524) (Breast Cancer Type 1 susceptibility Protein, RING Finger Protein 53, BRCA1, RNF53) discontinued
Sign In for Pricing
View Details 221099-02 100 µL
BRCA1, phosphorylated (S1524) (Breast Cancer Type 1 susceptibility Protein, RING Finger Protein 53, BRCA1, RNF53) discontinued
Sign In for Pricing
View Details LS084247-100ug 100 µg
RTL6 (NM_032287) Human Over-expression Lysate
Sign In for Pricing
View Details