CD275 polyclonal antibody
Product Specifications
Background
Ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion; induces also B-cell proliferation and differentiation into plasma cells. Could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co-stimulating memory T-cell function (By similarity) .
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Product Name Alternative
ICOS ligand; B7 homolog 2; B7-H2; B7-like protein Gl50; B7-related protein 1; B7RP-1; CD_antigen: CD275; ICOSLG; B7H2; B7RP1; ICOSL; KIAA0653
Swiss Prot
O75144
Reactivity
Human, Mouse
Immunogen
Recombinant protein of human CD275.
Conjugation
Unconjugated
Applications
WB IF
Dilution
WB: 1:1000~1:2000 IF 1:50~1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodified
Molecular Weight
~ 70 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
CD275 polyclonal antibody detects endogenous levels of CD275 protein.
Applications Notes
Western blot (WB) analysis of CD275 polyclonal antibody at 1:1000 dilution Lane1:L02 whole cell lysate (30ug) Lane2:SP2/0 cell membrane lysate (24ug) Lane3:HEK293T whole cell lysate (30ug)
Host or Source
Rabbit
Available Sizes
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