Integrin α3 (CD49c) polyclonal antibody
Product Specifications
Background
Integrin alpha-3/beta-1 is a receptor for fibronectin, laminin, collagen, epiligrin, thrombospondin and CSPG4. Integrin alpha-3/beta-1 provides a docking site for FAP (seprase) at invadopodia plasma membranes in a collagen-dependent manner and hence may participate in the adhesion, formation of invadopodia and matrix degradation processes, promoting cell invasion. Alpha-3/beta-1 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Product Name Alternative
Integrin alpha-3; CD49 antigen-like family member C; FRP-2; Galactoprotein B3; GAPB3; VLA-3 subunit alpha; CD_antigen: CD49c; Integrin alpha-3 heavy chain; Integrin alpha-3 light chain; ITGA3; MSK18
Swiss Prot
P26006
Reactivity
Human
Immunogen
Recombinant protein of human Integrin α3 (CD49c) .
Conjugation
Unconjugated
Applications
WB IF
Dilution
WB: 1:1000~1:2000 IF 1:50~1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodified
Molecular Weight
~ 116 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Integrin α3 (CD49c) polyclonal antibody detects endogenous levels of Integrin α3 (CD49c) protein.
Applications Notes
Western blot (WB) analysis of Integrin α3 (CD49c) polyclonal antibody at 1:1000 dilution Lane1:EC9706 whole cell lysate (30ug) Lane2:A549 whole cell lysate (30ug)
Host or Source
Rabbit
Available Sizes
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