Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

EGFR (phospho-Y1173) polyclonal antibody

Product Specifications

Background

EGFR is a receptor tyrosine kinase. Receptor for epidermal growth factor (EGF) and related growth factors including TGF-alpha, amphiregulin, betacellulin, heparin-binding EGF-like growth factor, GP30 and vaccinia virus growth factor. Is involved in the control of cell growth and differentiation. . A single-pass transmembrane tyrosine kinase. Ligand binding to this receptor results in receptor dimerization, autophosphorylation (in trans), activation of various downstream signaling molecules and lysosomal degradation.

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

EGFR; ERBB; ERBB1; HER1; Epidermal growth factor receptor; Proto-oncogene c-ErbB-1; Receptor tyrosine-protein kinase erbB-1

Swiss Prot

P00533

Reactivity

Human

Immunogen

KLH-conjugated synthetic phosphopeptide corresponding to residues surrounding Y1173 of human EGFR protein.

Conjugation

Unconjugated

Related Pathways

ErbB HER Signaling

Applications

WB, IHC, IF/ICC, IP

Dilution

WB: 1:500-1:1000 IHC: 1:50-1:100 IF/ICC: 1:50-1:100 IP: 1:50-1:100

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Modification

Phosphorylated

Molecular Weight

~ 160 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

EGFR (phospho-Y1173) polyclonal antibody detects endogenous levels of EGFR protein only when phosphorylated at Tyr1173.

Applications Notes

Western blot analysis of EGFR (Phospho-Y1173) expression in Hela (A), A549 (B) whole cell lysates.

Host or Source

Rabbit

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Recombinant Anti-UFM1 Rabbit mAb
CMA6613-01 30 µL

Recombinant Anti-UFM1 Rabbit mAb

Sign In for Pricing
View Details
Recombinant Anti-UFM1 Rabbit mAb
CMA6613-02 50 μL

Recombinant Anti-UFM1 Rabbit mAb

Sign In for Pricing
View Details
Recombinant Anti-UFM1 Rabbit mAb
CMA6613-03 100 µL

Recombinant Anti-UFM1 Rabbit mAb

Sign In for Pricing
View Details
Recombinant Anti-UFM1 Rabbit mAb
CMA6613-04 200 µL

Recombinant Anti-UFM1 Rabbit mAb

Sign In for Pricing
View Details
SARS Rabbit Polyclonal Antibody (Biotin)
orb2125123 100 µL

SARS Rabbit Polyclonal Antibody (Biotin)

Sign In for Pricing
View Details
Lentiviral mouse Dusp28 shRNA (UAS) - Lentiviral mouse Dusp28 shRNA (UAS, RFP) (25)
GTR15257723 1 Vial

Lentiviral mouse Dusp28 shRNA (UAS) - Lentiviral mouse Dusp28 shRNA (UAS, RFP) (25)

Sign In for Pricing
View Details