RRM2 polyclonal antibody
Product Specifications
Background
Ribonucleotide reductase M2 subunit is one of two subunits that constitute ribonucleotide reductase, the enzyme that catalyzes the conversion of ribonucleotide 5'-diphosphates into 2'-deoxyribonucleotides, a rate-limiting step in the production of 2'-deoxyribonucleoside 5'-diphosphates (dNTP) required for DNA synthesis and repair that is required for DNA synthesis and repair.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
R2; Ribonucleoside-diphosphate reductase subunit M2; Ribonucleotide reductase M2 subunit; Ribonucleotide reductase small chain; Ribonucleotide reductase small subunit; RIR2_HUMAN; RR2; RR2M; RRM2
Swiss Prot
P31350
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-70 of human RRM2 (NP_001025.1) .
Conjugation
Unconjugated
Applications
WB IHC-P IF/ICC IP
Dilution
WB 1:500 - 1:1000 IHC-P 1:50 - 1:200 IF/ICC 1:50 - 1:200 IP 1:50 - :1200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodified
Molecular Weight
~ 45 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
RRM2 polyclonal antibody detects endogenous levels of RRM2 protein.
Applications Notes
Western blot analysis of extracts of HeLa cells, using RRM2 antibody at 1:1000 dilution.
Host or Source
Rabbit
Available Sizes
Curated Selection
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