KDEL Rabbit monoclonal antibody

Product Specifications

Background

This receptor recognizes K-D-E-L.The sequence Lys-Asp-Glu-Leu (KDEL) or a closely related sequence, is present at the carboxy-terminus of soluble endoplasmic reticulum (ER) resident proteins and some membrane proteins. Determines the specificity of the luminal ER protein retention system.Required for the retention of luminal endoplasmic reticulum proteins. Determines the specificity of the luminal ER protein retention system. Also required for normal vesicular traffic through the Golgi.

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Product Name Alternative

KDEL; Lys Asp Glu Leu

Swiss Prot

P24390

Reactivity

Human, Rat, Mouse

Immunogen

A synthesized peptide derived from human KDEL

Conjugation

Unconjugated

Applications

WB, IHC, ICC/IF, FC

Dilution

WB 1:500~1:1000 IHC 1:50~1:200 ICC/IF 1:50~1:200 FC 1:50

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Modification

Unmodified

Molecular Weight

~ 90 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

KDEL Rabbit monoclonal antibody detects endogenous levels of KDEL protein.

Applications Notes

Western blot (WB) analysis of KDEL Rabbit monoclonal antibody at 1:500 dilution Lane1:K562 whole cell lysate (30ug) Lane2:Hela whole cell lysate (30ug)