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Phospho-Chk1 (S280) Rabbit monoclonal antibody

Product Specifications

Background

Serine/threonine-protein kinase which is required for checkpoint-mediated cell cycle arrest and activation of DNA repair in response to the presence of DNA damage or unreplicated DNA. May also negatively regulate cell cycle progression during unperturbed cell cycles.

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Product Name Alternative

Checkpoint kinase 1; Chek1; Chk1; rad27

Swiss Prot

O14757

Reactivity

Human

Immunogen

A synthesized peptide derived from human Phospho-Chk1 (S280)

Conjugation

Unconjugated

Applications

WB

Dilution

WB 1:500~1:2000

Purity

Affinity-chromatography

Modification

Phosphorylated

Molecular Weight

54kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

Phospho-Chk1 (S280) Antibody detects endogenous levels of total Phospho-Chk1 (S280)

Applications Notes

Western blot analysis of Phospho-Chk1 (S280) expression in 293T treated with Calyculin A cell lysate.

Host or Source

Rabbit

Available Sizes

Curated Selection

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