Phospho-Chk1 (S280) Rabbit monoclonal antibody
Product Specifications
Background
Serine/threonine-protein kinase which is required for checkpoint-mediated cell cycle arrest and activation of DNA repair in response to the presence of DNA damage or unreplicated DNA. May also negatively regulate cell cycle progression during unperturbed cell cycles.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Product Name Alternative
Checkpoint kinase 1; Chek1; Chk1; rad27
Swiss Prot
O14757
Reactivity
Human
Immunogen
A synthesized peptide derived from human Phospho-Chk1 (S280)
Conjugation
Unconjugated
Applications
WB
Dilution
WB 1:500~1:2000
Purity
Affinity-chromatography
Modification
Phosphorylated
Molecular Weight
54kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Phospho-Chk1 (S280) Antibody detects endogenous levels of total Phospho-Chk1 (S280)
Applications Notes
Western blot analysis of Phospho-Chk1 (S280) expression in 293T treated with Calyculin A cell lysate.
Host or Source
Rabbit
Available Sizes
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