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Phospho-Rb (S780) Rabbit monoclonal antibody

Product Specifications

Background

Key regulator of entry into cell division that acts as a tumor suppressor. Promotes G0-G1 transition when phosphorylated by CDK3/cyclin-C. Acts as a transcription repressor of E2F1 target genes.

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Product Name Alternative

OSRC; Osteosarcoma; P105RB; PP105; pp110; PPP1R130; Prepro retinoblastoma associated protein; RB transcriptional corepressor 1; RB1; Retinoblastoma 1; Retinoblastoma suspectibility protein

Swiss Prot

P06400

Reactivity

Human Mouse

Immunogen

A synthesized peptide derived from human Phospho-Rb (S780)

Conjugation

Unconjugated

Applications

WB

Dilution

WB 1:500~1:2000

Purity

Affinity-chromatography

Modification

Phosphorylated

Molecular Weight

106kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

Phospho-Rb (S780) Antibody detects endogenous levels of total Phospho-Rb (S780)

Applications Notes

Western blot analysis of Phospho-Rb (S780) expression in K562 cell lysate.

Host or Source

Rabbit

Available Sizes

Curated Selection

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