SOCS7 Rabbit monoclonal antibody
Product Specifications
Background
Regulates signaling cascades probably through protein ubiquitination and/or sequestration. Functions in insulin signaling and glucose homeostasis through IRS1 ubiquitination and subsequent proteasomal degradation. Inhibits also prolactin, growth hormone and leptin signaling by preventing STAT3 and STAT5 activation, sequestering them in the cytoplasm and reducing their binding to DNA.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Product Name Alternative
Ash and phospholipase C gamma-binding protein; NAP4; Nck; Nck Ash and phospholipase C binding protein; Nck associated protein 4; NCKAP4; SH2 domain containing SOCS box protein; SOCS4; SOCS6; Socs7; Suppressor of cytokine signaling 7
Swiss Prot
O14512
Reactivity
Human
Immunogen
A synthesized peptide derived from human SOCS7
Conjugation
Unconjugated
Applications
WB IHC
Dilution
WB 1:500~1:2000 IHC 1:50~1:200
Purity
Affinity-chromatography
Modification
Unmodified
Molecular Weight
63kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
SOCS7 Antibody detects endogenous levels of total SOCS7
Applications Notes
Western blot analysis of SOCS7 expression in HeLa cell lysate.
Host or Source
Rabbit
Available Sizes
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