Phospho-c-Jun (S73) +JunD (S100) Rabbit monoclonal antibody
Product Specifications
Background
Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3' (PubMed:10995748, PubMed:22083952) . Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation (PubMed:17210646) . Involved in activated KRAS-mediated transcriptional activation of USP28 in colorectal cancer (CRC) cells (PubMed:24623306) . Binds to the USP28 promoter in colorectal cancer (CRC) cells (PubMed:24623306) .
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Product Name Alternative
JunD; c-Jun
Swiss Prot
P05412, P17535
Reactivity
Human Mouse
Immunogen
A synthesized peptide derived from human Phospho-c-Jun (S73) +JunD (S100)
Conjugation
Unconjugated
Applications
WB IHC IP
Dilution
WB 1:500~1:2000 IHC 1:50~1:200 IP 1:50
Purity
Affinity-chromatography
Modification
Phosphorylated
Molecular Weight
38,42,45kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Phospho-c-Jun (S73) +JunD (S100) Antibody detects endogenous levels of total Phospho-c-Jun (S73) +JunD (S100)
Applications Notes
Western blot analysis of Phospho-c-Jun (S73) +JunD (S100) expression in RAW 264.7 cell lysate.
Host or Source
Rabbit
Available Sizes
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