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Phospho-MLKL (S345) Rabbit monoclonal antibody

Product Specifications

Background

Pseudokinase that plays a key role in TNF-induced necroptosis, a programmed cell death process (PubMed:22265413, PubMed:22265414, PubMed:22421439, PubMed:24316671) .

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Product Name Alternative

HMLKL ; Mixed lineage kinase domain like; Mixed lineage kinase domain like protein; Mixed lineage kinase domain like pseudokinase

Swiss Prot

Q9D2Y4 (Mouse)

Reactivity

Mouse

Immunogen

A synthesized peptide derived from human Phospho-MLKL (S345)

Conjugation

Unconjugated

Applications

WB IP

Dilution

WB 1:500~1:2000 IP 1:50

Purity

Affinity-chromatography

Modification

Phosphorylated

Molecular Weight

54kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

Phospho-MLKL (S345) Antibody detects endogenous levels of total Phospho-MLKL (S345)

Applications Notes

Western blot analysis of Phospho-MLKL (S345) expression in (1) L929 treated with Z-VAD + TNF alpha + SM164 cell lysate; (2) Untreated.

Host or Source

Rabbit

Available Sizes

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