PAG Rabbit monoclonal antibody
Product Specifications
Background
Negatively regulates TCR (T-cell antigen receptor) -mediated signaling in T-cells and FCER1 (high affinity immunoglobulin epsilon receptor) -mediated signaling in mast cells. Promotes CSK activation and recruitment to lipid rafts, which results in LCK inhibition. Inhibits immunological synapse formation by preventing dynamic arrangement of lipid raft proteins.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Product Name Alternative
CBP; Csk binding protein; PAG; PAG1
Swiss Prot
Q9NWQ8
Reactivity
Human Mouse Rat
Immunogen
A synthesized peptide derived from human PAG
Conjugation
Unconjugated
Applications
WB IHC IP FC
Dilution
WB 1:500~1:2000 IHC 1:50~1:200 IP 1:50 FC 1:100
Purity
Affinity-chromatography
Modification
Unmodified
Molecular Weight
80kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
PAG Antibody detects endogenous levels of total PAG
Applications Notes
Western blot analysis of PAG expression in Raji cell lysate.
Host or Source
Rabbit
Available Sizes
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