Smg1 Rabbit monoclonal antibody
Product Specifications
Background
Serine/threonine protein kinase involved in both mRNA surveillance and genotoxic stress response pathways. Recognizes the substrate consensus sequence [ST]-Q. Plays a central role in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons by phosphorylating UPF1/RENT1.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Product Name Alternative
61E3.4; ATX; hSMG1; LIP; smg1
Swiss Prot
Q96Q15
Reactivity
Human Mouse Rat
Immunogen
A synthesized peptide derived from human Smg1
Conjugation
Unconjugated
Applications
WB
Dilution
WB 1:500~1:2000
Purity
Affinity-chromatography
Modification
Unmodified
Molecular Weight
410kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Smg1 Antibody detects endogenous levels of total Smg1
Applications Notes
Western blot analysis of Smg1 expression in Saos2 cell lysate.
Host or Source
Rabbit
Available Sizes
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