DOK1 Rabbit monoclonal antibody
Product Specifications
Background
DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK1 appears to be a negative regulator of the insulin signaling pathway. Modulates integrin activation by competing with talin for the same binding site on ITGB3.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Product Name Alternative
DOK1; p62 (dok) ; P62DOK; pp62
Swiss Prot
Q99704
Reactivity
Human Mouse Rat
Immunogen
A synthesized peptide derived from human DOK1
Conjugation
Unconjugated
Applications
WB ICC/IF
Dilution
WB 1:500~1:2000 ICC/IF 1:50~1:200
Purity
Affinity-chromatography
Modification
Unmodified
Molecular Weight
65kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
DOK1 Antibody detects endogenous levels of total DOK1
Applications Notes
Western blot analysis of DOK1 expression in K562 cell lysate.
Host or Source
Rabbit
Available Sizes
Curated Selection
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